At the recent Paleo Diet Seminar - Loren Cordain shared his thoughts about taking supplements. While he did say that there can be problems associated with consuming large amounts of isolated nutrients, there were two supplements that he did recommend. The first is EPA/DHA Omega-3 Fatty Acids because most of the lean meats we consume are lacking in these "good" fats. The other is a nutrient that our bodies produces as a result of sun exposure and unless you get 15-30 minutes of direct sunlight, take Vitamin D.